ESMR: Methodological Aspects and Preliminary Experience at Vilnius University Hospital
Objectives: To study the safety and effect of serial extracorporeal shockwave myocardial revascularization (ESMR) on patients’ symptoms and parameters of left ventricular function. Methods and results: the study group consisted of 16 patients (pts) with end-stage coronary artery disease (CAD), mostly after revascularization, in whom angina pectoris (AP) persisted despite optimal medical therapy. Prospective analysis data were collected from 16 patients (3 women, 13 men) with end-stage CAD (3-vessel disease) and AP CCS III-IV, 15/16 pts were after...
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Initial Clinical Experience With Extracorporeal Shock Wave Therapy in Treatment of Ischemic Heart Failure
Yury A. Vasyuk MD, Alla B. Hadzegova MD, Evgeny L. Shkolnik MD, Maya V. Kopeleva MD, Olga V. Krikunova MD, Elena N. Iouchtchouk MD, Elena M. Aronova MD, Svetlana V. Ivanova MD Previous experimental studies have suggested a beneficial effect of extracorporeal shock wave therapy (ESWT) in patients with ischemic heart failure. Twenty-four patients with ischemic heart failure and left ventricular ejection fraction (LVEF) less than 40% received ESWT in addition to their stable treatment. ESWT was performed in 9 sessions with 100 shocks per spot in...
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Extracorporeal Shock Wave Therapy Reverses Ischemia-Related Left Ventricular Dysfunction and Remodeling: Molecular-Cellular and Functional Assessment
By Fu M, Sun C-K, Lin Y-C, Wang C-J, Wu C-J, et al. (2011) An optimal treatment for patients with diffuse obstructive arterial disease unsuitable for catheter-based or surgical intervention is still pending. This study tested the hypothesis that extracorporeal shock wave (ECSW) therapy may be a therapeutic alternative under such clinical situation. Myocardial ischemia was induced in male mini-pigs through applying an ameroid constrictor over mid-left anterior descending artery (LAD). Twelve mini-pigs were equally randomized into group 1...
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ESMR improves clinical symptoms and left ventricular function in patients with refractory angina
Zuozienė G, Laucevičius A, Leibowitz D. Vilnius University Clinic of Cardiovascular Diseases, Vilnius, Lithuania. BACKGROUND: Medical therapy for refractory angina is limited and the prognosis is poor. Experimental data suggest that the use of extracorporeal shockwave myocardial revascularization (ESMR) can contribute to angiogenesis and improve symptoms of angina and left ventricular (LV) function. The objective of this study was to examine the effects of ESMR on clinical symptoms as well as LV function as assessed by cardiac MRI in...
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